SECISBP2L

Across TCGA patient cohorts, SECISBP2L protein abundance is significantly associated with the RNA expression of many other genes, with 10,723 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SECISBP2L-associated genes across cancer lineages are DMBT1, FBXO27, and APH1B. Each is linked with SECISBP2L in more than 2 cancer types. Because this analysis shows association rather than direction, both SECISBP2L-to-partner and partner-to-SECISBP2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SECISBP2L versus DMBT1 in COAD, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SECISBP2L→partner) and Y-score (partner→SECISBP2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DMBT1 →	+2.605	+0.463	.009	.002	3	3
LSCC	FBXO27 →	-1.152	-0.191	.001	.009	3	3
LSCC	APH1B →	+0.484	+0.262	<.001	<.001	3	3
LSCC	FABP4 →	+1.370	+0.157	<.001	<.001	3	3
LSCC	UTP25 →	-0.394	-0.182	<.001	<.001	3	2
COAD	MALL →	+1.023	+0.426	.006	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,723 associations by consensus.

SECISBP2L vs DMBT1 — COAD

Explore this scatter interactively →