SEC61G-DT

Across TCGA patient cohorts, SEC61G-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,993 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SEC61G-DT-associated GO terms across cancer lineages are Mitochondrial translation, Mitochondrial respiratory chain complex assembly, and Protein maturation by iron-sulfur cluster transfer. Each is linked with SEC61G-DT in more than 17 cancer types. Because this analysis shows association rather than direction, both SEC61G-DT-to-partner and partner-to-SEC61G-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by SEC61G-DT-low versus SEC61G-DT-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC61G-DT→partner) and Y-score (partner→SEC61G-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitochondrial translation →	+0.067	+0.308	.001	<.001	3	18
ESCA	Mitochondrial respiratory chain complex assembly →	+0.067	+0.317	.001	.001	3	16
ESCA	Protein maturation by iron-sulfur cluster transfer →	+0.060	+0.253	.001	.006	1	17
ESCA	Mitochondrial gene expression →	+0.069	+0.289	<.001	.001	3	15
ESCA	Peptidyl-lysine modification →	+0.063	+0.325	<.001	<.001	3	14
ESCA	Intraciliary anterograde transport →	+0.047	+0.247	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,993 associations by consensus.

Mitochondrial translation by SEC61G-DT expression — ESCA

Explore this box plot interactively →