SEC61A2

Across TCGA patient cohorts, SEC61A2 RNA expression is significantly associated with the RNA expression of many other genes, with 21,215 significant associations in total. ACC shows the largest number of these associations.

The most reproducible SEC61A2-associated genes across cancer lineages are LARP4B, CHD6, and USP6NL. Each is linked with SEC61A2 in more than 32 cancer types. Because this analysis shows association rather than direction, both SEC61A2-to-partner and partner-to-SEC61A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC61A2 versus LARP4B in ACC, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC61A2→partner) and Y-score (partner→SEC61A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	LARP4B →	+1.103	+0.926	<.001	<.001	3	33
TGCT	CHD6 →	+1.134	+0.838	<.001	<.001	3	33
DLBC	USP6NL →	+1.056	+0.935	<.001	.001	3	33
UVM	MINDY3 →	+1.323	+1.047	<.001	<.001	3	33
ACC	SUV39H2 →	+1.143	+1.005	<.001	<.001	3	33
DLBC	OTUD3 →	+1.138	+1.296	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,215 associations by consensus.

SEC61A2 vs LARP4B — ACC

Explore this scatter interactively →