SEC23B

Across TCGA patient cohorts, SEC23B protein abundance is significantly associated with the RNA expression of many other genes, with 17,572 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEC23B-associated genes across cancer lineages are TIMP3, TGFB1I1, and SCHIP1. Each is linked with SEC23B in more than 8 cancer types. Because this analysis shows association rather than direction, both SEC23B-to-partner and partner-to-SEC23B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC23B versus TIMP3 in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC23B→partner) and Y-score (partner→SEC23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TIMP3 →	-1.746	-0.336	<.001	.003	3	9
OV	TGFB1I1 →	-1.147	-0.358	<.001	<.001	3	9
UCEC	SCHIP1 →	-0.633	-0.295	<.001	<.001	3	9
HNSC	SEC11C →	+0.977	+0.354	<.001	<.001	3	9
COAD	MSRB3 →	-1.206	-0.251	<.001	<.001	3	9
BRCA	SEC23A →	-0.762	-0.350	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,572 associations by consensus.

SEC23B vs TIMP3 — OV

Explore this scatter interactively →