SEC23B

Across TCGA cell cohorts, SEC23B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,669 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SEC23B-associated GO terms across cancer lineages are Regulation of protein localization to endoplasmic reticulum, Positive regulation of protein localization to endoplasmic reticulum, and Regulation of plasma cell differentiation. Each is linked with SEC23B in more than 14 cancer types. Because this analysis shows association rather than direction, both SEC23B-to-partner and partner-to-SEC23B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to endoplasmic reticulum grouped by SEC23B-low versus SEC23B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC23B→partner) and Y-score (partner→SEC23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of protein localization to endoplasmic reticulum →	+0.156	+1.003	<.001	.002	3	15
OESOPHAGUS	Positive regulation of protein localization to endoplasmic reticulum →	+0.143	+0.972	<.001	.003	3	14
KIDNEY	Regulation of plasma cell differentiation →	+0.191	+0.934	<.001	.001	3	11
KIDNEY	Positive regulation of plasma cell differentiation →	+0.177	+0.934	<.001	.001	3	11
SKIN	2-oxoglutarate decarboxylation to succinyl-CoA →	+0.115	+0.798	<.001	.001	3	10
SKIN	Cytosolic transport →	+0.065	+0.630	<.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,669 associations by consensus.

Regulation of protein localization to endoplasmic reticulum by SEC23B expression — OESOPHAGUS

Explore this box plot interactively →