SEC22B2P

Across TCGA pan-cancer cohorts, SEC22B2P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated SEC22B2P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher SEC22B2P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SEC22B2P expression acts as an unfavorable survival marker, although some lineages such as COAD and MESO show a favorable association.

UCS, THCA, and READ are the cancer types where SEC22B2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
THCA	OS	Tertile	IV	0.753	1.000	<.001	33	view →
READ	DFS	Tertile	II,III,IV	0.141	0.548	<.001	27	view →
STAD	DFS	Quartile	IV	0.135	0.533	.009	23	view →
ACC	OS	Tertile	All	0.614	0.848	.015	21	view →
KIRP	OS	Tertile	All	0.832	0.959	.011	15	view →
KICH	DFS	Quartile	All	0.541	0.911	.021	12	view →
COAD	DFS	Tertile	IV	0.653	0.247	.028	9	view →
MESO	OS	Tertile	IV	1.000	0.310	.037	6	view →
LUSC	OS	Tertile	III,IV	0.708	0.284	.030	6	view →
THYM	OS	Tertile	II,III,IV	0.578	0.879	.023	3	view →
UVM	DFS	Tertile	All	1.000	0.705	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

SEC22B2P–UCS (DFS)

Open the UCS breakdown →