SDR9C7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SDR9C7 mutation is significantly associated with the RNA expression of many other genes, with 316 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDR9C7-associated genes across cancer lineages are RPL27P5, RPL31P9, and COX6CP7. Each is linked with SDR9C7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR9C7-to-partner and partner-to-SDR9C7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL27P5 grouped by SDR9C7-low versus SDR9C7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR9C7→partner) and Y-score (partner→SDR9C7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRPL27P5 →+0.295+3.313<.001.00832
COADRPL31P9 →+0.259+4.721<.001.00432
COADCOX6CP7 →+0.235+3.686.008.00532
UCECCHURC1-FNTB →+0.068+2.736<.001.00132
LUADDIS3L2P1 →+0.108+4.572.003<.00132
LUSCCHEK2P5 →+0.229+5.792.006.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 316 associations by consensus.

RPL27P5 by SDR9C7 expression — COAD

Box plot of RPL27P5 in SDR9C7-low vs SDR9C7-high samples in COAD.

Explore this box plot interactively →

Exploration