SDR9C7

Across TCGA pan-cancer cohorts, SDR9C7 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SDR9C7’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SDR9C7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SDR9C7 is over-expressed in tumor, although a few such as READ and COAD show the opposite, repressed pattern.

LUSC, KIRC, and READ are the cancer types where SDR9C7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SDR9C7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+1.659	<.001	7	view →
KIRC	Male	All	+0.023	.006	3	view →
READ	Female	All	−0.096	.021	2	view →
LIHC	Male	All	+0.051	.046	1	view →
THCA	All	All	+0.032	.033	1	view →
COAD	All	All	−0.024	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SDR9C7–LUSC

Open the LUSC breakdown →