SDHAF4

Across TCGA cell cohorts, SDHAF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,406 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SDHAF4-associated GO terms across cancer lineages are Respiratory chain complex II assembly, Mitochondrial respiratory chain complex II assembly, and 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process. Each is linked with SDHAF4 in more than 16 cancer types. Because this analysis shows association rather than direction, both SDHAF4-to-partner and partner-to-SDHAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Respiratory chain complex II assembly grouped by SDHAF4-low versus SDHAF4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHAF4→partner) and Y-score (partner→SDHAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Respiratory chain complex II assembly →	+0.166	+1.210	<.001	<.001	3	17
LUNG_SCLC	Mitochondrial respiratory chain complex II assembly →	+0.166	+1.210	<.001	<.001	3	17
SOFT_TISSUE	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.098	+0.897	<.001	<.001	3	11
CNS	Vesicle targeting, rough ER to cis-Golgi →	+0.081	+0.694	<.001	.001	3	9
PANCREAS	Protein import into peroxisome matrix →	+0.074	+0.800	.004	.003	3	9
PANCREAS	Protein transmembrane import into intracellular organelle →	+0.074	+0.800	.004	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,406 associations by consensus.

Respiratory chain complex II assembly by SDHAF4 expression — LUNG_SCLC

Explore this box plot interactively →