SDC3

Across TCGA patient cohorts, SDC3 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,099 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SDC3-associated proteins across cancer lineages are UQCRC2, SERPINF1, and EEF2. Each is linked with SDC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SDC3-to-partner and partner-to-SDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDC3 versus UQCRC2 in COAD, with a Pearson correlation of 0.64.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SDC3→partner) and Y-score (partner→SDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	UQCRC2 →	+0.414	+0.957	<.001	<.001	3	3
OV	SERPINF1 →	-0.737	-0.626	<.001	<.001	3	3
PDAC	EEF2 →	-0.292	-2.209	<.001	<.001	3	3
PDAC	LSP1_S252 →	-0.628	-1.579	.001	<.001	3	3
PDAC	HSPB1_S82 →	-1.015	-2.000	<.001	<.001	3	3
PDAC	NDUFC1 →	+0.631	+1.958	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,099 associations by consensus.

SDC3 vs UQCRC2 — COAD

Explore this scatter interactively →