SCUBE2

Across TCGA cell cohorts, SCUBE2 RNA expression is significantly associated with the RNA expression of many other genes, with 7,991 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SCUBE2-associated genes across cancer lineages are DSTYK, MAN1B1, and ATP6AP2. Each is linked with SCUBE2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SCUBE2-to-partner and partner-to-SCUBE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCUBE2 versus DSTYK in SKIN, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCUBE2→partner) and Y-score (partner→SCUBE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DSTYK →	+1.561	+1.706	<.001	<.001	3	6
BONE	MAN1B1 →	+1.129	+0.788	<.001	.002	3	5
BONE	ATP6AP2 →	+1.273	+0.796	<.001	<.001	3	5
LIVER	UCK1 →	+0.799	+0.682	<.001	<.001	3	5
STOMACH	DLGAP4 →	+1.042	+0.690	<.001	.001	2	6
BONE	PLA2G15 →	+1.383	+0.741	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,991 associations by consensus.

SCUBE2 vs DSTYK — SKIN

Explore this scatter interactively →