SCRN3

Across TCGA patient cohorts, SCRN3 mutation is significantly associated with the RNA expression of many other genes, with 2,460 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCRN3-associated genes across cancer lineages are SNRPGP19, SLCO1B1, and FAM204DP. Each is linked with SCRN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCRN3-to-partner and partner-to-SCRN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP19 grouped by SCRN3-low versus SCRN3-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCRN3→partner) and Y-score (partner→SCRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SNRPGP19 →	+0.126	+5.091	<.001	.003	3	2
UCEC	SLCO1B1 →	+0.273	+1.741	<.001	.003	3	2
LIHC	FAM204DP →	+0.067	+4.293	<.001	.009	3	2
LUSC	FABP5P4 →	+0.499	+4.993	<.001	.002	3	2
UCEC	RN7SL402P →	+0.124	+2.136	.001	.001	3	2
BRCA	CA15P2 →	+0.053	+5.122	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,460 associations by consensus.

SNRPGP19 by SCRN3 expression — LIHC

Explore this box plot interactively →