SCNN1B

Across TCGA patient cohorts, SCNN1B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,543 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCNN1B-associated proteins across cancer lineages are RRP36_S73, ZKSCAN8_S193, and CEACAM7. Each is linked with SCNN1B in more than 3 cancer types. Because this analysis shows association rather than direction, both SCNN1B-to-partner and partner-to-SCNN1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCNN1B versus RRP36_S73 in UCEC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCNN1B→partner) and Y-score (partner→SCNN1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRP36_S73 →	-0.827	-1.797	<.001	<.001	3	4
UCEC	ZKSCAN8_S193 →	-0.475	-1.189	.005	.005	3	4
LSCC	CEACAM7 →	+1.469	+1.643	.004	.003	3	4
LSCC	CLCA4 →	+1.199	+1.113	<.001	<.001	3	4
COAD	COBLL1_S788 →	+0.609	+1.130	<.001	<.001	3	4
UCEC	TST →	+0.704	+1.624	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,543 associations by consensus.

SCNN1B vs RRP36_S73 — UCEC

Explore this scatter interactively →