SCNN1A

Across TCGA cell cohorts, SCNN1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,892 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SCNN1A-associated GO terms across cancer lineages are Sensory perception of salty taste, Sensory perception of sour taste, and Response to vasopressin. Each is linked with SCNN1A in more than 15 cancer types. Because this analysis shows association rather than direction, both SCNN1A-to-partner and partner-to-SCNN1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sensory perception of salty taste grouped by SCNN1A-low versus SCNN1A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCNN1A→partner) and Y-score (partner→SCNN1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Sensory perception of salty taste →	+1.863	+5.952	<.001	<.001	3	16
URINARY_TRACT	Sensory perception of sour taste →	+1.766	+3.658	<.001	<.001	3	13
STOMACH	Response to vasopressin →	+0.261	+2.950	<.001	<.001	3	12
STOMACH	Cellular response to vasopressin →	+0.261	+2.950	<.001	<.001	3	12
STOMACH	Response to acidic pH →	+0.179	+2.942	<.001	.002	3	11
OESOPHAGUS	Negative regulation of protein polymerization →	+0.135	+3.120	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,892 associations by consensus.

Sensory perception of salty taste by SCNN1A expression — LUNG_SCLC

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