SCIN

Across TCGA patient cohorts, SCIN RNA expression is significantly associated with the protein abundance of many other proteins, with 16,175 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCIN-associated proteins across cancer lineages are ABLIM1, FAM83E_S351, and TOP1. Each is linked with SCIN in more than 4 cancer types. Because this analysis shows association rather than direction, both SCIN-to-partner and partner-to-SCIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCIN versus ABLIM1 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCIN→partner) and Y-score (partner→SCIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABLIM1 →	+0.358	+1.230	<.001	<.001	3	5
PDAC	FAM83E_S351 →	+0.963	+1.040	<.001	<.001	3	5
UCEC	TOP1 →	-0.411	-0.763	<.001	<.001	3	5
HNSC	TACC1 →	+0.318	+0.727	<.001	.001	3	5
HNSC	ARFGEF3 →	+0.595	+0.845	<.001	.001	3	4
LSCC	ZFHX3_S3432 →	+0.402	+0.896	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,175 associations by consensus.

SCIN vs ABLIM1 — LSCC

Explore this scatter interactively →