SCGB1C1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SCGB1C1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCGB1C1-associated genes across cancer lineages are EPPIN, ACTRT1, and TRIM42. Each is linked with SCGB1C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB1C1-to-partner and partner-to-SCGB1C1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB1C1→partner) and Y-score (partner→SCGB1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaEPPIN →+0.006+4.922.005.00931
BLOOD_LeukemiaACTRT1 →+0.038+5.201<.001.00631
BLOOD_LeukemiaTRIM42 →+0.006+4.922<.001.00931
BLOOD_LeukemiaKRTAP12-3 →+0.113+5.539<.001.00331
BLOOD_LeukemiaOR1P1 →+0.203+4.922<.001.00931
BLOOD_LeukemiaOR1D5 →+0.039+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

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