SCG2

Across TCGA patient cohorts, SCG2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,868 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCG2-associated genes across cancer lineages are CDH19, SST, and CHGA. Each is linked with SCG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCG2-to-partner and partner-to-SCG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCG2 versus CDH19 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCG2→partner) and Y-score (partner→SCG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDH19 →	+1.050	+0.566	<.001	.001	3	4
LUAD	SST →	+3.506	+1.726	.004	<.001	3	4
BRCA	CHGA →	+4.764	+1.698	.002	.004	3	4
BRCA	SCG3 →	+3.521	+1.870	.001	.005	3	4
BRCA	KCNK3 →	+2.207	+1.638	.004	.007	3	4
GBM	NPY →	+1.192	+0.576	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,868 associations by consensus.

SCG2 vs CDH19 — GBM

Explore this scatter interactively →