SCG2

Across TCGA cell cohorts, SCG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,972 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SCG2-associated GO terms across cancer lineages are Ganglion development, Calcium-independent cell-matrix adhesion, and Golgi vesicle transport. Each is linked with SCG2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SCG2-to-partner and partner-to-SCG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ganglion development grouped by SCG2-low versus SCG2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCG2→partner) and Y-score (partner→SCG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Ganglion development →	+0.248	+2.612	<.001	<.001	3	7
PANCREAS	Calcium-independent cell-matrix adhesion →	+0.168	+2.673	.001	.002	3	7
SKIN	Golgi vesicle transport →	+0.054	+2.130	<.001	<.001	3	7
URINARY_TRACT	Positive regulation of synapse structural plasticity →	+1.039	+0.942	.002	.007	3	6
URINARY_TRACT	Aorta smooth muscle tissue morphogenesis →	+0.971	+1.114	.001	.003	3	6
URINARY_TRACT	Positive regulation of cell-substrate junction organization →	+0.146	+1.659	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,972 associations by consensus.

Ganglion development by SCG2 expression — LIVER

Explore this box plot interactively →