SCAMP3

Across TCGA patient cohorts, SCAMP3 mutation is significantly associated with the RNA expression of many other genes, with 2,745 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCAMP3-associated genes across cancer lineages are LINC01318, TMEM259, and NGRN. Each is linked with SCAMP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCAMP3-to-partner and partner-to-SCAMP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01318 grouped by SCAMP3-low versus SCAMP3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAMP3→partner) and Y-score (partner→SCAMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC01318 →	+0.111	+4.631	.004	.008	3	3
UCEC	TMEM259 →	+0.387	+3.480	.007	.002	3	2
UCEC	NGRN →	+0.452	+3.480	.007	.002	3	2
UCEC	NDUFA6 →	+0.457	+3.854	<.001	<.001	3	2
UCEC	PARPBP →	+0.571	+3.321	.003	<.001	3	2
UCEC	CIDECP1 →	+0.369	+3.716	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,745 associations by consensus.

LINC01318 by SCAMP3 expression — LUAD

Explore this box plot interactively →