SCAMP2

Across TCGA cell cohorts, SCAMP2 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCAMP2-associated genes across cancer lineages are OR6C76, PRAMEF7, and ZNF705G. Each is linked with SCAMP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCAMP2-to-partner and partner-to-SCAMP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C76 grouped by SCAMP2-low versus SCAMP2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAMP2→partner) and Y-score (partner→SCAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR6C76 →	+0.062	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	PRAMEF7 →	+0.098	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ZNF705G →	+0.006	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	TEX51 →	+0.026	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	PRAMEF4 →	+0.139	+4.867	<.001	.009	3	1
LARGE_INTESTINE	KLF18 →	+0.012	+4.930	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

OR6C76 by SCAMP2 expression — BLOOD_Lymphoma

Explore this box plot interactively →