SAV1

Across TCGA patient cohorts, SAV1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,601 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SAV1-associated proteins across cancer lineages are SEC23B, GOLGA2, and ARFGEF2. Each is linked with SAV1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SAV1-to-partner and partner-to-SAV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAV1 versus SEC23B in CCRCC, with a Pearson correlation of -0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAV1→partner) and Y-score (partner→SAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEC23B →	-0.403	-0.429	<.001	<.001	3	5
GBM	GOLGA2 →	-0.195	-0.244	.008	.001	3	5
BRCA	ARFGEF2 →	-0.325	-0.477	.002	.003	3	5
LSCC	TRMT5 →	+0.357	+0.437	<.001	<.001	3	5
CCRCC	CSDE1_S514 →	-0.633	-0.445	.006	<.001	3	5
CCRCC	ZNF622 →	-0.385	-0.342	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,601 associations by consensus.

SAV1 vs SEC23B — CCRCC

Explore this scatter interactively →