SAV1

Across TCGA patient cohorts, SAV1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,102 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SAV1-associated genes across cancer lineages are LYVE1, FKBP11, and RALGPS1. Each is linked with SAV1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SAV1-to-partner and partner-to-SAV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAV1 versus LYVE1 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAV1→partner) and Y-score (partner→SAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LYVE1 →	+1.778	+0.541	<.001	<.001	3	3
CCRCC	FKBP11 →	-0.460	-0.201	<.001	<.001	3	3
GBM	RALGPS1 →	-0.599	-0.374	.004	.001	3	3
GBM	SAA1 →	+2.173	+0.440	.002	.003	3	3
LSCC	FERMT2 →	+0.591	+0.213	.001	.001	3	3
LSCC	CNIH1 →	+0.425	+0.234	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,102 associations by consensus.

SAV1 vs LYVE1 — GBM

Explore this scatter interactively →