SAT1

Across TCGA patient cohorts, SAT1 mutation is significantly associated with the RNA expression of many other genes, with 1,066 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAT1-associated genes across cancer lineages are BNIP3P6, RNA5SP422, and CYP4F36P. Each is linked with SAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAT1-to-partner and partner-to-SAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P6 grouped by SAT1-low versus SAT1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAT1→partner) and Y-score (partner→SAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BNIP3P6 →	+0.143	+7.057	<.001	.009	3	2
UCEC	RNA5SP422 →	+0.624	+1.764	<.001	.007	3	2
BRCA	CYP4F36P →	+0.116	+4.986	<.001	.003	3	1
HNSC	RN7SKP55 →	+0.126	+5.241	.003	.007	3	1
UCEC	INTS4 →	+0.297	+1.880	.008	.005	3	1
UCEC	ADAM33 →	-0.858	-3.647	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,066 associations by consensus.

BNIP3P6 by SAT1 expression — BRCA

Explore this box plot interactively →