SARS1

Across TCGA cell cohorts, SARS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,367 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SARS1-associated GO terms across cancer lineages are L-amino acid biosynthetic process, Tyrosine transport, and L-leucine import across plasma membrane. Each is linked with SARS1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SARS1-to-partner and partner-to-SARS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-amino acid biosynthetic process grouped by SARS1-low versus SARS1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SARS1→partner) and Y-score (partner→SARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	L-amino acid biosynthetic process →	+0.123	+1.008	.001	.001	3	11
SOFT_TISSUE	Tyrosine transport →	+0.240	+0.718	.001	.005	3	11
PANCREAS	L-leucine import across plasma membrane →	+0.215	+1.047	<.001	<.001	3	11
BLOOD_Myeloma	Negative regulation of translation in response to endoplasmic reticulum stress →	+0.200	+1.190	.004	.002	2	11
BLOOD_Lymphoma	Amino acid biosynthetic process →	+0.115	+1.334	<.001	<.001	3	10
LARGE_INTESTINE	Alpha-amino acid biosynthetic process →	+0.080	+0.849	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,367 associations by consensus.

L-amino acid biosynthetic process by SARS1 expression — PANCREAS

Explore this box plot interactively →