SAR1AP4

Across TCGA patient cohorts, SAR1AP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,403 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SAR1AP4-associated GO terms across cancer lineages are Positive regulation of proteasomal protein catabolic process, Regulatory ncRNA processing, and Protein desumoylation. Each is linked with SAR1AP4 in more than 8 cancer types. Because this analysis shows association rather than direction, both SAR1AP4-to-partner and partner-to-SAR1AP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal protein catabolic process grouped by SAR1AP4-low versus SAR1AP4-high in COAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAR1AP4→partner) and Y-score (partner→SAR1AP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Positive regulation of proteasomal protein catabolic process →	+0.032	+0.033	<.001	.003	3	9
STAD	Regulatory ncRNA processing →	+0.023	+0.029	.001	.003	3	8
CESC	Protein desumoylation →	+0.040	+0.029	<.001	<.001	3	8
CESC	Midbrain development →	+0.027	+0.029	<.001	<.001	3	8
LUSC	N-terminal protein amino acid modification →	+0.022	+0.032	<.001	.003	3	8
STAD	Regulation of protein sumoylation →	+0.036	+0.054	.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,403 associations by consensus.

Positive regulation of proteasomal protein catabolic process by SAR1AP4 expression — COAD

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