SAR1AP4

Across TCGA pan-cancer cohorts, SAR1AP4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SAR1AP4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SAR1AP4 RNA is repressed in tumor relative to normal tissue. In most cancer types SAR1AP4 is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and LUSC are the cancer types where SAR1AP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SAR1AP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.056	.001	6	view →
LUAD	All	III,IV	−0.092	.003	4	view →
LUSC	Male	All	−0.047	.003	3	view →
THCA	Male	IV	−0.240	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SAR1AP4–KIRC

Open the KIRC breakdown →