SAP30BP

Across TCGA patient cohorts, SAP30BP mutation is significantly associated with the RNA expression of many other genes, with 451 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAP30BP-associated genes across cancer lineages are MIR6803, RPL36AP6, and GNG5P5. Each is linked with SAP30BP in more than 1 cancer types. Because this analysis shows association rather than direction, both SAP30BP-to-partner and partner-to-SAP30BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by SAP30BP-low versus SAP30BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP30BP→partner) and Y-score (partner→SAP30BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.197	+4.893	<.001	.001	3	2
UCEC	RPL36AP6 →	+0.114	+2.713	<.001	.002	3	2
UCEC	GNG5P5 →	+0.145	+2.567	.008	.008	3	2
UCEC	VWA8P1 →	+0.097	+3.885	<.001	.008	3	2
UCEC	RNU6-751P →	+0.144	+4.151	<.001	.006	3	2
LUSC	RNU6-1277P →	+0.345	+5.133	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 451 associations by consensus.

MIR6803 by SAP30BP expression — UCEC

Explore this box plot interactively →