SAP30BP

Across TCGA pan-cancer cohorts, SAP30BP RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SAP30BP data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SAP30BP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SAP30BP expression acts as an unfavorable survival marker, although some lineages such as THYM and CHOL show a favorable association.

ACC, LIHC, and KIRP are the cancer types where SAP30BP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	II,III,IV	0.741	0.971	<.001	98	view →
LIHC	DFS	Median	All	0.457	0.622	<.001	68	view →
KIRP	DFS	Quartile	III,IV	0.182	0.692	.003	63	view →
PRAD	DFS	Quartile	All	0.652	0.912	<.001	32	view →
THYM	OS	Median	All	1.000	0.768	.003	24	view →
MESO	OS	Tertile	IV	0.238	0.858	.004	18	view →
KIRC	DFS	Median	IV	0.228	0.472	.010	15	view →
BLCA	DFS	Tertile	All	0.556	0.778	.020	12	view →
CHOL	OS	Quartile	All	0.955	0.241	.010	12	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	11	view →
UCEC	DFS	Median	All	0.802	0.870	.011	10	view →
LGG	DFS	Median	All	0.342	0.459	.005	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

SAP30BP–ACC (OS)

Open the ACC breakdown →