SAMD9L

Across TCGA cell cohorts, SAMD9L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,922 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SAMD9L-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Positive regulation of canonical NF-kappaB signal transduction, and Cytolysis in another organism. Each is linked with SAMD9L in more than 18 cancer types. Because this analysis shows association rather than direction, both SAMD9L-to-partner and partner-to-SAMD9L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by SAMD9L-low versus SAMD9L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD9L→partner) and Y-score (partner→SAMD9L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytoplasmic pattern recognition receptor signaling pathway →	+0.082	+2.276	<.001	<.001	3	19
LIVER	Positive regulation of canonical NF-kappaB signal transduction →	+0.063	+1.473	.004	.005	3	18
LUNG_NSCLC_LUSC	Cytolysis in another organism →	+1.648	+2.434	<.001	<.001	3	17
SOFT_TISSUE	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.300	+1.411	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Intracellular receptor signaling pathway →	+0.058	+2.185	.001	.003	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of viral process →	+0.151	+1.991	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,922 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by SAMD9L expression — BONE

Explore this box plot interactively →