SAMD9L

Across TCGA cell cohorts, SAMD9L mutation is significantly associated with the RNA expression of many other genes, with 331 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SAMD9L-associated genes across cancer lineages are OC90, APOC4, and EPB42. Each is linked with SAMD9L in more than 2 cancer types. Because this analysis shows association rather than direction, both SAMD9L-to-partner and partner-to-SAMD9L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OC90 grouped by SAMD9L-low versus SAMD9L-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD9L→partner) and Y-score (partner→SAMD9L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OC90 →	+0.031	+3.786	<.001	.004	3	3
LUNG_NSCLC_LUAD	APOC4 →	+0.028	+3.944	<.001	.006	3	3
OESOPHAGUS	EPB42 →	+0.050	+3.432	.001	.001	3	2
OESOPHAGUS	CNPY1 →	+0.112	+3.115	.003	.005	3	2
SKIN	CFAP46 →	+0.462	+2.497	<.001	.008	3	2
SOFT_TISSUE	KRTAP2-4 →	+0.147	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 331 associations by consensus.

OC90 by SAMD9L expression — PANCREAS

Explore this box plot interactively →