SAMD15

Across TCGA patient cohorts, SAMD15 mutation is significantly associated with the RNA expression of many other genes, with 2,555 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAMD15-associated genes across cancer lineages are RN7SL782P, OR5D16, and PYDC2. Each is linked with SAMD15 in more than 2 cancer types. Because this analysis shows association rather than direction, both SAMD15-to-partner and partner-to-SAMD15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL782P grouped by SAMD15-low versus SAMD15-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD15→partner) and Y-score (partner→SAMD15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL782P →	+0.100	+5.874	<.001	.001	3	3
SKCM	OR5D16 →	+0.016	+3.990	.001	.009	3	2
LUAD	PYDC2 →	+0.356	+4.712	<.001	.007	3	2
LUAD	OR9L1P →	+0.067	+4.984	<.001	.005	3	2
LUAD	MIR5000 →	+0.668	+4.399	<.001	.006	3	2
LIHC	RNU6-452P →	+0.472	+5.008	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,555 associations by consensus.

RN7SL782P by SAMD15 expression — BRCA

Explore this box plot interactively →