Q-omics provides the consensus-scored MIR5000 profile across patient tissues and cancer cell-line models. MIR5000 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, MIR5000 is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, MIR5000 RNA expression shows 6,035 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight COAD, THCA, and STAD as cancer lineages where MIR5000 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR5000 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR5000 survival associations across molecular data types. MIR5000 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR5000 RNA expression–survival associations across cancer types. High MIR5000 expression shows unfavorable associations in COAD, READ, KIRP, LUSC, SARC and KIRC. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for MIR5000 RNA expression.
This table summarizes MIR5000 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR5000. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR5000 shows lower tumor expression in THCA. The THCA box plot shows higher MIR5000 RNA expression in normal versus tumor tissue (log2 FC = −0.171, t-test p = .009).
This table shows molecular features associated with MIR5000 in patient tissues and cancer cell lines. In patient samples, MIR5000 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
