MIR5000

Across TCGA pan-cancer cohorts, MIR5000 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MIR5000 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR5000 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR5000 expression acts as an unfavorable survival marker, although some lineages such as THCA and BLCA show a favorable association.

COAD, READ, and KIRP are the cancer types where MIR5000 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.114	0.574	<.001	108	view →
READ	OS	Tertile	IV	0.424	0.764	.009	48	view →
KIRP	OS	Tertile	All	0.688	0.912	<.001	39	view →
LUSC	OS	Tertile	III,IV	0.219	0.575	.021	27	view →
SARC	OS	Tertile	All	0.309	0.837	<.001	18	view →
KIRC	OS	Quartile	All	0.520	0.687	.005	15	view →
THCA	DFS	Tertile	II,III,IV	1.000	0.701	.031	15	view →
BLCA	DFS	Tertile	III,IV	0.711	0.314	.012	9	view →
ACC	OS	Tertile	All	0.477	0.808	.031	9	view →
LUAD	OS	Tertile	III,IV	0.223	0.676	.040	9	view →
LIHC	OS	Tertile	III,IV	0.204	0.648	.030	9	view →
ESCA	OS	Tertile	IV	0.743	0.398	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MIR5000–COAD (DFS)

Open the COAD breakdown →