SALL3

Across TCGA cell cohorts, SALL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 711 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SALL3-associated GO terms across cancer lineages are Chromosomal 5-methylcytosine DNA demethylation pathway, Gastrulation, and Cellular response to xenobiotic stimulus. Each is linked with SALL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SALL3-to-partner and partner-to-SALL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal 5-methylcytosine DNA demethylation pathway grouped by SALL3-low versus SALL3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SALL3→partner) and Y-score (partner→SALL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.110	+1.587	.005	.004	3	5
BREAST	Gastrulation →	-0.084	-0.076	<.001	.005	3	4
LUNG_SCLC	Cellular response to xenobiotic stimulus →	-0.061	-1.694	<.001	<.001	3	4
BREAST	Regulation of heart contraction →	-0.050	-0.105	.003	.007	3	4
LUNG_SCLC	Regulation of heterochromatin formation →	+0.180	+2.155	<.001	<.001	3	4
LUNG_SCLC	Regulation of heterochromatin organization →	+0.115	+1.381	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 711 associations by consensus.

Chromosomal 5-methylcytosine DNA demethylation pathway by SALL3 expression — LUNG_SCLC

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