SAGE1

Across TCGA patient cohorts, SAGE1 protein abundance is significantly associated with the RNA expression of many other genes, with 525 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAGE1-associated genes across cancer lineages are SBF1, PCK2, and PCIF1. Each is linked with SAGE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAGE1-to-partner and partner-to-SAGE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAGE1 versus SBF1 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAGE1→partner) and Y-score (partner→SAGE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SBF1 →	+0.807	+1.494	<.001	.001	3	1
LSCC	PCK2 →	+0.869	+1.010	.009	.003	3	1
LSCC	PCIF1 →	+0.427	+1.168	.002	<.001	3	1
LSCC	PROCR →	+0.988	+1.214	.008	.009	3	1
LSCC	CCDC22 →	+0.881	+1.280	.001	.001	3	1
LSCC	ZNF629 →	+0.545	+0.998	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 525 associations by consensus.

SAGE1 vs SBF1 — LSCC

Explore this scatter interactively →