SAC3D1

Across TCGA patient cohorts, SAC3D1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,146 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAC3D1-associated proteins across cancer lineages are RRM1, MCM3, and NASP. Each is linked with SAC3D1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SAC3D1-to-partner and partner-to-SAC3D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAC3D1 versus RRM1 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAC3D1→partner) and Y-score (partner→SAC3D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RRM1 →	+0.596	+0.689	<.001	<.001	3	9
BRCA	MCM3 →	+0.670	+0.719	<.001	.006	3	8
OV	NASP →	+0.525	+0.525	<.001	<.001	3	8
LSCC	RFC2 →	+0.450	+0.700	<.001	<.001	3	7
OV	RIF1_S2348 →	+1.009	+0.747	<.001	<.001	3	7
UCEC	RRM2 →	+0.758	+1.005	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,146 associations by consensus.

SAC3D1 vs RRM1 — LSCC

Explore this scatter interactively →