SAC3D1

Across TCGA pan-cancer cohorts, SAC3D1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of SAC3D1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SAC3D1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SAC3D1 is over-expressed in tumor.

BLCA, HNSC, and KIRP are the cancer types where SAC3D1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SAC3D1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Female	All	+1.470	<.001	12	view →
HNSC	Male	III,IV	+1.301	<.001	12	view →
KIRP	Male	III,IV	+1.107	<.001	11	view →
COAD	Female	All	+1.207	<.001	10	view →
LIHC	Male	II,III,IV	+1.868	<.001	9	view →
STAD	Male	III,IV	+1.521	<.001	9	view →
LUAD	All	III,IV	+1.057	<.001	9	view →
KIRC	All	III,IV	+0.417	<.001	9	view →
LUSC	Female	II,III,IV	+1.854	<.001	8	view →
THCA	All	II,III,IV	+0.638	<.001	7	view →
UCEC	All	III,IV	+1.450	<.001	6	view →
BRCA	All	III,IV	+1.107	<.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

SAC3D1–BLCA

Open the BLCA breakdown →