SAC3D1

Across TCGA patient cohorts, SAC3D1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,408 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAC3D1-associated genes across cancer lineages are GTSE1, PRMT5, and CDKN3. Each is linked with SAC3D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SAC3D1-to-partner and partner-to-SAC3D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAC3D1 versus GTSE1 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAC3D1→partner) and Y-score (partner→SAC3D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GTSE1 →	+1.191	+0.375	<.001	<.001	3	4
LSCC	PRMT5 →	+0.453	+0.271	<.001	.001	3	3
UCEC	CDKN3 →	+1.290	+0.400	<.001	<.001	3	3
BRCA	MCM4 →	+0.762	+0.389	.001	.002	3	3
UCEC	DLGAP5 →	+1.640	+0.351	<.001	<.001	3	3
LSCC	EMC8 →	+0.364	+0.269	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,408 associations by consensus.

SAC3D1 vs GTSE1 — UCEC

Explore this scatter interactively →