SAC3D1

Across TCGA patient cohorts, SAC3D1 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,551 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAC3D1-associated proteins across cancer lineages are NUF2_S247, BUB1B, and CCNB1. Each is linked with SAC3D1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SAC3D1-to-partner and partner-to-SAC3D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAC3D1 versus NUF2_S247 in PDAC, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAC3D1→partner) and Y-score (partner→SAC3D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NUF2_S247 →	+1.261	+0.460	<.001	<.001	3	5
UCEC	BUB1B →	+0.860	+0.451	<.001	<.001	3	4
UCEC	CCNB1 →	+0.861	+0.289	<.001	<.001	3	4
UCEC	DLGAP5 →	+0.949	+0.347	<.001	<.001	3	4
UCEC	NCAPD2 →	+0.533	+0.303	<.001	<.001	3	4
UCEC	PRIM1 →	+0.562	+0.324	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,551 associations by consensus.

SAC3D1 vs NUF2_S247 — PDAC

Explore this scatter interactively →