SAC3D1

Across TCGA patient cohorts, SAC3D1 mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAC3D1-associated genes across cancer lineages are RNU6-1318P, RN7SL454P, and CDT1. Each is linked with SAC3D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAC3D1-to-partner and partner-to-SAC3D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1318P grouped by SAC3D1-low versus SAC3D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAC3D1→partner) and Y-score (partner→SAC3D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1318P →	+0.503	+3.551	<.001	<.001	3	2
UCEC	RN7SL454P →	+0.241	+2.575	<.001	.006	3	2
UCEC	CDT1 →	+0.857	+3.354	.005	.005	3	1
UCEC	ZBTB8OS →	+0.431	+3.354	.003	.005	3	1
COAD	OR9Q2 →	+0.030	+4.721	.004	.004	3	1
COAD	LUADT1 →	+0.287	+3.313	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

RNU6-1318P by SAC3D1 expression — UCEC

Explore this box plot interactively →