SAC3D1

Across TCGA patient cohorts, SAC3D1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAC3D1-associated genes across cancer lineages are Preadipocytes, Sebocytes, and CD8+ naive T-cells. Each is linked with SAC3D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAC3D1-to-partner and partner-to-SAC3D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by SAC3D1-low versus SAC3D1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAC3D1→partner) and Y-score (partner→SAC3D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Preadipocytes →	+0.039	+3.169	.002	.015	3	1
UCEC	Sebocytes →	+0.035	+3.083	.006	.016	3	1
UCEC	CD8+ naive T-cells →	+0.043	+3.364	.002	.005	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Preadipocytes by SAC3D1 expression — COAD

Explore this box plot interactively →