SAC3D1

Across TCGA cell cohorts, SAC3D1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,286 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SAC3D1-associated genes across cancer lineages are ITSN2, CDR2, and HDAC5. Each is linked with SAC3D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SAC3D1-to-partner and partner-to-SAC3D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAC3D1 versus ITSN2 in OVARY, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAC3D1→partner) and Y-score (partner→SAC3D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ITSN2 →	+0.977	+1.369	<.001	.001	3	4
OESOPHAGUS	CDR2 →	-0.552	-1.418	.001	<.001	3	3
OVARY	HDAC5 →	-1.927	-1.589	<.001	.002	3	3
LUNG_SCLC	IFTAP →	-2.237	-0.976	.002	.001	3	3
PANCREAS	C15orf48 →	+6.129	+1.472	<.001	.003	3	3
BLOOD_Lymphoma	ATP6V0E1 →	+1.498	+1.646	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,286 associations by consensus.

SAC3D1 vs ITSN2 — OVARY

Explore this scatter interactively →