SAA2-SAA4

Across TCGA patient cohorts, SAA2-SAA4 mutation is significantly associated with the RNA expression of many other genes, with 337 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAA2-SAA4-associated genes across cancer lineages are RNA5SP408, OR1X1P, and MRPS36P5. Each is linked with SAA2-SAA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAA2-SAA4-to-partner and partner-to-SAA2-SAA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP408 grouped by SAA2-SAA4-low versus SAA2-SAA4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA2-SAA4→partner) and Y-score (partner→SAA2-SAA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP408 →	+0.328	+3.017	.002	.003	3	2
LIHC	OR1X1P →	+0.042	+5.268	<.001	.006	3	1
LIHC	MRPS36P5 →	+0.185	+5.268	.004	.006	3	1
LIHC	LINC00929 →	+0.273	+5.268	<.001	.006	3	1
BLCA	BNIP3P13 →	+0.121	+5.788	<.001	.003	3	1
HNSC	MIR449A →	+0.368	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 337 associations by consensus.

RNA5SP408 by SAA2-SAA4 expression — UCEC

Explore this box plot interactively →