Q-omics provides the consensus-scored MIR449A profile across patient tissues and cancer cell-line models. MIR449A expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in OV. Additionally, MIR449A RNA expression shows 6,764 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight OV, and ESCA as cancer lineages where MIR449A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR449A survival associations across molecular data types. MIR449A RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR449A data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	OV (90)	view →

This table ranks reproducible MIR449A RNA expression–survival associations across cancer types. High MIR449A expression shows unfavorable associations in OV, THCA, SKCM, HNSC and PRAD, but favorable associations in LUAD. The OV Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify OV as the clearest survival context for MIR449A RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	All	0.266	0.391	.005	90	view →
THCA	DFS	Tertile	All	0.107	0.830	<.001	81	view →
SKCM	DFS	Tertile	All	0.016	0.758	<.001	72	view →
HNSC	OS	Tertile	All	0.198	0.768	.001	18	view →
PRAD	OS	Tertile	All	0.946	0.990	.018	6	view →
LUAD	DFS	Tertile	All	1.000	0.334	.045	3	view →

Pink = unfavorable, green = favorable. all 6 lineages →

MIR449A-OV (DFS)

Kaplan–Meier survival curve for MIR449A RNA expression in OV: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR449A in patient tissues and cancer cell lines. In patient samples, MIR449A shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	6,764	ESCA (3222)	view →
Function (RNA)	4,241	STAD (3854)	view →