Across TCGA patient cohorts, MIR449A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,241 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR449A-associated GO terms across cancer lineages are Spermatid differentiation, N-terminal protein amino acid acetylation, and Protein localization to cilium. Each is linked with MIR449A in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR449A-to-partner and partner-to-MIR449A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR449A→partner) and Y-score (partner→MIR449A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	Spermatid differentiation →	+0.035	+0.133	<.001	<.001	3	5
STAD	N-terminal protein amino acid acetylation →	+0.136	+0.035	<.001	.001	3	5
STAD	Protein localization to cilium →	+0.093	+0.036	<.001	.001	3	4
STAD	Microtubule-based transport →	+0.123	+0.071	<.001	<.001	3	4
STAD	Positive regulation of plasma membrane bounded cell projection assembly →	+0.139	+0.067	<.001	<.001	3	4
STAD	Mitochondrial gene expression →	+0.213	+0.035	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,241 associations by consensus.

Exploration

MIR449A survival (RNA) · tumor vs normal (RNA) · all MIR449A data types