SAA1

Across TCGA patient cohorts, SAA1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,078 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAA1-associated genes across cancer lineages are S100A12, PROK2, and FCAR. Each is linked with SAA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SAA1-to-partner and partner-to-SAA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAA1 versus S100A12 in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA1→partner) and Y-score (partner→SAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	S100A12 →	+1.280	+1.459	<.001	<.001	3	6
COAD	PROK2 →	+0.970	+0.589	<.001	<.001	3	6
PDAC	FCAR →	+0.714	+0.967	<.001	.001	2	6
GBM	MEFV →	+0.860	+1.394	<.001	<.001	3	5
GBM	ADGRE3 →	+0.840	+1.150	<.001	<.001	3	4
BRCA	SAA2 →	+1.978	+0.937	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,078 associations by consensus.

SAA1 vs S100A12 — GBM

Explore this scatter interactively →