SAA1

Across TCGA cell cohorts, SAA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,821 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SAA1-associated GO terms across cancer lineages are Vertebrate eye-specific patterning, Antigen processing and presentation of endogenous peptide antigen via MHC class I, and Positive regulation of complement activation. Each is linked with SAA1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SAA1-to-partner and partner-to-SAA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vertebrate eye-specific patterning grouped by SAA1-low versus SAA1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA1→partner) and Y-score (partner→SAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vertebrate eye-specific patterning →	+1.863	+3.049	<.001	<.001	3	13
BREAST	Antigen processing and presentation of endogenous peptide antigen via MHC class I →	+0.252	+2.678	<.001	<.001	3	13
STOMACH	Positive regulation of complement activation →	+2.012	+2.972	<.001	.001	3	13
OVARY	Positive regulation of cytokine-mediated signaling pathway →	+0.094	+3.401	.002	.005	3	13
URINARY_TRACT	Complement-mediated synapse pruning →	+1.673	+3.588	<.001	<.001	3	12
URINARY_TRACT	Complement activation, GZMK pathway →	+1.675	+3.737	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,821 associations by consensus.

Vertebrate eye-specific patterning by SAA1 expression — STOMACH

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