S100Z

Across TCGA patient cohorts, S100Z RNA expression is significantly associated with the protein abundance of many other proteins, with 19,164 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible S100Z-associated proteins across cancer lineages are ANKRD44, WIPF1, and ELMO1. Each is linked with S100Z in more than 8 cancer types. Because this analysis shows association rather than direction, both S100Z-to-partner and partner-to-S100Z results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S100Z versus ANKRD44 in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (S100Z→partner) and Y-score (partner→S100Z) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD44 →	+0.542	+0.306	<.001	.001	3	9
OV	WIPF1 →	+0.517	+0.322	<.001	.001	3	9
GBM	ELMO1 →	+0.571	+0.527	<.001	<.001	3	9
OV	SIPA1 →	+0.343	+0.392	<.001	.001	3	8
GBM	HCLS1 →	+0.701	+0.492	<.001	<.001	3	8
GBM	KCTD12 →	+0.635	+0.584	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,164 associations by consensus.

S100Z vs ANKRD44 — OV

Explore this scatter interactively →