S100P

Across TCGA patient cohorts, S100P protein abundance is significantly associated with the RNA expression of many other genes, with 11,770 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible S100P-associated genes across cancer lineages are LCN2, FCGR3B, and CEACAM3. Each is linked with S100P in more than 6 cancer types. Because this analysis shows association rather than direction, both S100P-to-partner and partner-to-S100P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S100P versus LCN2 in UCEC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100P→partner) and Y-score (partner→S100P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LCN2 →	+2.654	+1.427	<.001	<.001	3	7
LSCC	FCGR3B →	+1.358	+1.231	<.001	<.001	3	7
LSCC	CEACAM3 →	+0.681	+1.484	<.001	<.001	3	7
HNSC	FFAR2 →	+0.962	+1.097	.007	.001	3	6
GBM	S100A12 →	+1.413	+1.561	<.001	<.001	3	6
UCEC	LIPH →	+1.169	+1.067	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,770 associations by consensus.

S100P vs LCN2 — UCEC

Explore this scatter interactively →