S100G

Across TCGA patient cohorts, S100G mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100G-associated genes across cancer lineages are FRG2, AK4P2, and MIR6744. Each is linked with S100G in more than 1 cancer types. Because this analysis shows association rather than direction, both S100G-to-partner and partner-to-S100G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FRG2 grouped by S100G-low versus S100G-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100G→partner) and Y-score (partner→S100G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FRG2 →	+0.048	+5.283	.003	.006	3	1
COAD	AK4P2 →	+0.138	+5.212	<.001	.007	3	1
COAD	MIR6744 →	+1.289	+5.602	<.001	.004	3	1
UCEC	SLCO1B1 →	+0.725	+3.085	<.001	.005	3	1
UCEC	C17orf77 →	+1.121	+3.471	<.001	.008	3	1
UCEC	PLA2G2E →	+0.313	+2.956	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

FRG2 by S100G expression — COAD

Explore this box plot interactively →